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Vangenes Cell-Free DNA BCT

Vangenes Cell-Free DNA BCT

Price: THB 0
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TEST DETAILS

Description

Vangenes Cell-Free DNA Blood Collection Tube (BCT) is a direct draw whole blood collection tube intended for collection, stabilization and transportation of cell-free plasma or serum DNA and cellular genomic DNA present in nucleated cells.

DESCRIPTION AND APPLICATION

The implications of cell-free DNA (cfDNA) in blood in clinical medicine have been known since 1997. cfDNA extracted from plasma of cancer patients has shown characteristics typical of tumor DNA and may serve as non-invasive biomarkers for cancer detection and management. It has also been demonstrated that cfDNA extracted from blood plasma of pregnant mothers contain fetal cfDNA. Clinical applications involving fetal cfDNA analysis include sex determination, single-gene disorders and aneuploidy detection.

Due to the low abundance of the cfDNA biomarkers of cancer or fetal origin, it is recommended that genomic DNA background levels be minimized to provide accurate measurements cfDNA levels.

The mixing cell protective reagent contained in Vangenes Cell-Free DNA BCT can stabilize nucleated blood cells, preventing the release of cellular genomic DNA, inhibiting nuclease mediated degradation of cf-DNA, and contribute to the overall stabilization of cf-DNA.

Blood samples collected in Vangenes Cell-Free DNA BCT are stable for up to 14 days when stored at the recommended temperature range of 6-37°C.

ADVANTAGES OF USE:

  • CE marked
  • China FDA Approved
  • CNAS certification for safe transport
  • Sample transport and storage at room temperature for up to 14 days
  • contains the anticoagulant K3EDTA and a mixing cell protective reagent in a liquid medium
  • Available in glass or plastic tubes
  • Colors of hemogard and stopper customizable

Important Information

REAGENTS

Vangenes Cell-Free DNA BCT contains the anticoagulant K3EDTA and a mixing cell protective reagent in a liquid medium.

STORAGE AND STABILITY

1. When stored at 18-30°C, Vangenes Cell-Free DNA BCT is stable through expiration date.
2. Blood samples collected in Vangenes Cell-Free DNA BCT for cf-DNA analysis are stable for 14 days when stored between 6-37°C.
3. Blood samples collected in Vangenes Cell-Free DNA BCT for cf-DNA analysis are stable for 72 hours if transported between 6-37°C.
4. Do not freeze unfilled Vangenes Cell-Free DNA BCT.
5. During extreme temperature conditions, Vangenes Cell-Free DNA BCT needs proper insulation for shipment.

INSTRUCTIONS FOR USE

1. Collect specimen by venipuncture according to WS/T225-2002.
2. Since Vangenes Cell-Free DNA BCT contains chemical additives, it is very important to avoid possible backflow from the tube.
3. Fill tube completely.
4. Remove tube from adapter and immediately mix by gently inversion 8-10 times. One inversion is a complete turn of the wrist, 180 degrees, and back.
5. After collection, transport and store tubes within the recommended temperature range(6-37°C).
6. Perform extraction in accordance with instrument manufacturer’s instructions.

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