Clinical DNA test for cancers that may be inherited or passed down to your children. These include the analysis of 50 genes (Breast, Ovary, Uterine, Colorectal, Melanomas, Pancreatic, Gastric, Prostate, NEM, Pheochromocytoma, Paraganglioma, Retinoblastoma, and Renal cancers). We use the latest in Next Generation Sequencing (NGS) technology and the kits are CE IVD marked. Only a simple buccal sample is required.

Sample type: 5ml peripheral blood in EDTA or 4 buccal swabs

Cancer types include:
Breast, Ovary, Uterine, Colorectal, Melanomas, Pancreatic, Gastric, Prostate, NEM, Pheochromocytoma, Paraganglioma, Retinoblastoma, Renal

50 genes tested:
MLH1, MSH2, MSH6, BRCA1, BRCA2, CDH1, RET, CDKN2A, NF1, SDHB, SDHD, APC, RB1, VHL, TP53, SDHC, STK11, ATM, MUTYH, FH, RAD51C, MEN1, PMS2, PTEN, SMAD4, BMPR1A, PALB2, CDK4, EPCAM, KIF1B, MET, NBN, PIK3CA, MRE11, BARD1, RAD51D, SDHA, POLE, POLD1, RAD50, CHEK2, SDHAF2, MAX, TMEM127, NTHL1, BRIP1, XRCC2, MLH3, MSH3, ABRAXAS1.

NGS technology
✓ Capture kit based on biotinylated probes
✓ Detection of SNVs, indels, CNVs and ALU insertions
✓ Datagenomics: Bioinformatics software included
✓ CE IVD marked
✓ STID: Sample tracking identification system
✓ 10ng of DNA from blood or buccal swab samples
✓ Coverage 99.5% (50X)
✓ Uniformity:
– 99.2% of the regions covered at > 0.2x of the mean
– 90.0% of the regions covered at > 0.5x of the mean
✓ Specificity: > 99.9%

PTC Laboratories Thailand only provides testing and does not provide any genetic counselling. The patient must seek the advice of a genetic counsellor to get guidance on reading and interpreting the report.